Thermo-sensitive-type high-strength tissue adhesive

• Main Authors: QU SHUXIN, ZHANG CHUNGU, SHAN LIANHAI, XIONG XIONG
• Format: Patent
• Language: Chinese; English
• Published: 12.07.2019
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP

The invention belongs to the technical field of tissue adhesives and particularly relates to a thermo-sensitive-type high-strength tissue adhesive. The problems are solved that in the prior art, the curing time of the tissue adhesive is long, and it is difficult to accurately control the curing time. According to the technical scheme, the tissue adhesive is prepared from, by weight, 75-90 parts ofa bionic adhesive and 10-25 parts of a thermo-sensitive micelle carried with an oxidizing agent. The bionic adhesive is prepared through copolymerization of dopamine methacrylamide and acrylic acid methoxyethyl ethyl ester, and the thermo-sensitive micelle is prepared through copolymerization of polyethylene glycol, 1,3-bis(carboxyl phenoxyl)propane and sebacic acid. An application method of thethermo-sensitive-type high-strength tissue adhesive comprises the steps that the injured part is coated or injected with the tissue adhesive, after being restored and fixed, the injured part is gluedthrough the adhesive, then