Method for extracting dehydroepiandrosterone from sweet potatoes

• Main Authors: PAN SIYI, ZOU DAN, WANG LUFENG, XU XIAOYUN
• Format: Patent
• Language: Chinese; English
• Published: 28.06.2019
• Subjects: CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY; STEROIDS

The invention discloses a method for extracting dehydroepiandrosterone from sweet potatoes. The method comprises the following steps: pre-conversion, acid hydrolysis, extraction, purification and thelike. According to the method, aiming at the defect that the product yield is very low because combined dioscin and cellulose cannot be completely separated by virtue of traditional acid hydrolysis, red potato pulp is stirred with treatment liquid, cellulose is adequately swelled, after mechanical grinding, hydrogen bonds and partial glucosidic bonds, combined with dioscin, of the sweet potatoe cellulose are broken, and dioscin is separated, so that the subsequent acid hydrolysis velocity and DHEA velocity are increased, and DHEA in the sweet potatoes is rapidly and efficiently extracted. 本发明公开了一种从红薯中提取脱氢表雄酮的方法，包括预转化处理、酸水解和提取、纯化等步骤。本发明针对传统酸水解无法将结合的薯蓣皂甙与纤维素完全分离，导致产物得率很低的缺陷，通过将红薯浆用处理液进行搅拌，使其纤维素充分润胀并在机械研磨处理后使红薯纤维素与薯蓣皂甙相结合的氢键和部分糖苷键断裂，促使薯蓣皂甙分离出来，从而提高了后续酸水解的速率和DHEA的提取率，达到快速、高效提取红薯中DHEA的目的。