Method for simultaneously extracting high-purity naringin and neohesperidin from fructus aurantii

• Main Authors: XIE GUANGWEI, LIN ZILI, XU HONGMEI, XIE XIANQI, HE CONGLIN, XIA SHIWEN, YANG XIAOXIA
• Format: Patent
• Language: Chinese; English
• Published: 21.06.2019
• Subjects: CHEMISTRY; DERIVATIVES THEREOF; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; SUGARS

The invention provides a method for simultaneously preparing high-purity naringin and neohesperidin from fructus aurantii. Essential oil in the fructus aurantii is extracted by a supercritical CO2 extraction technology at first, and then a naringin and neohesperidin crude extract mixture is extracted by the supercritical CO2 extraction technology. The crude extract mixture is separated and purified by macroporous adsorption resin to obtain the naringin and the neohesperidin. The method provided by the invention has the advantages of high extraction rate, high product purity, environmental friendliness and low cost, and is suitable for industrial production of high-purity naringin and neohesperidin. 本发明提供一种从枳壳中同时制备高纯度柚皮苷与新橙皮苷的方法。首先采用超临界CO2萃取技术提取枳壳中的挥发油，然后采用超临界CO2萃取技术提取柚皮苷和新橙皮粗提混合物。粗提混合物经大孔吸附树脂分离纯化后得到柚皮苷和新橙皮苷。本发明提供的方法具有提取率高，产品纯度高，环境友好，成本低廉的优点，适合高纯度柚皮苷和新橙皮苷的工业化生产。