Method simultaneously used for qualitative and quantitative analysis of main components of dibutyl preparation

• Main Authors: LIANG ZIMIN, GUO HAIJIAO, QIN JIEPING
• Format: Patent
• Language: Chinese; English
• Published: 07.06.2019
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention provides a detection method simultaneously used for the qualitative fingerprint spectrum analysis of a dibutyl preparation and the quantitative analysis of five main components of the dibutyl preparation. According to the detection method, a test solution is prepared through 60% ethanol reflux extraction; octadecylsilane bonded silica gel is adopted as a fixed phase, and acetonitrile-water is adopted as a mobile phase; a specific ultraviolet dual-wavelength time series conversion sampling mode is adopted; and the characteristic qualitative fingerprint spectrum of the preparationand the content of the five main active components of the preparation can be measured with just one chromatographic condition required. Scientific experiments prove that the method has the advantagesof simplicity, rapidity, high repeatability, high stability, strong fingerprint spectrum characteristics and accurate content measurement results, and can be used for the quality control of dibutyl preparation products such as