Ultrasonic-magnetic resonance imaging bimodal contrast agent and preparation method and application thereof

• Main Authors: HUANG YUESHAN, LAN JUN, LAO YONGHUA, DENG HUILIANG
• Format: Patent
• Language: Chinese; English
• Published: 24.05.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MEDICAL OR VETERINARY SCIENCE; NANOTECHNOLOGY; PERFORMING OPERATIONS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; TRANSPORTING

The invention belongs to the field of medical preparations and discloses an ultrasonic-magnetic resonance imaging bimodal contrast agent and a preparation method and application thereof. The ultrasonic-magnetic resonance imaging bimodal contrast agent is prepared by steps: mixing an ultrasonic imaging component and a magnetic resonance imaging component to form a kernel oil phase; mixing the kernel oil phase with a water phase to form primary emulsion; adding a solvent oil phase into the primary emulsion, adding a surfactant, stirring, adding a cross-linking agent and curing; after curing is finished, standing, settling, washing, centrifuging, collecting solid and drying to obtain the ultrasonic-magnetic resonance imaging bimodal contrast agent. The ultrasonic-magnetic resonance imaging bimodal contrast agent has an imaging enhancement function in ultrasonic imaging and magnetic resonance imaging and is capable of increasing the image resolution in ultrasonic and magnetic resonance imaging. 本发明属于医用配制品领域，公开了一种