用于鉴定和分离循环肿瘤细胞的磷脂醚类似物

本发明涉及鉴定循环肿瘤细胞、分离循环肿瘤细胞和实现循环肿瘤细胞下游分析的方法,其包括:使受试者的血液样品或血清样品与包含磷脂醚类似物的组合物接触,所述磷脂醚类似物与发光分子或磁珠键合;以及对受试者的血液样品或血清样品进行荧光显微术、流式细胞术或磁性分离。 The present invention is directed to a method of identifying, isolating, and enabling downstream analysis of circulating tumor cells comprising contacting a blood or blood...

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Format Patent
LanguageChinese
Published 03.03.2023
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Summary:本发明涉及鉴定循环肿瘤细胞、分离循环肿瘤细胞和实现循环肿瘤细胞下游分析的方法,其包括:使受试者的血液样品或血清样品与包含磷脂醚类似物的组合物接触,所述磷脂醚类似物与发光分子或磁珠键合;以及对受试者的血液样品或血清样品进行荧光显微术、流式细胞术或磁性分离。 The present invention is directed to a method of identifying, isolating, and enabling downstream analysis of circulating tumor cells comprising contacting a blood or blood serum sample of a subject with a composition comprising a phospholipid ether analog bound to a luminescent molecule or a magnetic bead and subjecting the blood or blood serum sample of the subject to fluorescent microscopy, flow cytometry or magnetic isolation.
Bibliography:Application Number: CN201780048543