COMPOUNDS AND METHODS OF PROMOTING MYELINATION
A method of promoting the generation of oligodendrocytes from oligodendrocyte precursor cells by enhancing their survival and/or maturation includes administering to the cell an effective amount of anagent that enhances and/or induces accumulation of delta8,9-unsaturated sterol intermediates of the...
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| Main Authors | , , , , |
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| Format | Patent |
| Language | Chinese English |
| Published |
21.05.2019
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| Subjects | |
| Online Access | Get full text |
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| Abstract | A method of promoting the generation of oligodendrocytes from oligodendrocyte precursor cells by enhancing their survival and/or maturation includes administering to the cell an effective amount of anagent that enhances and/or induces accumulation of delta8,9-unsaturated sterol intermediates of the cholesterol biosynthesis pathway in the oligodendrocyte precursor cells.
本申请涉及通过增强其存活和/或成熟促进少突胶质细胞从少突胶质细胞前体细胞产生的方法，包括向细胞给药有效量的增强和/或诱导少突胶质细胞前体细胞中胆固醇生物合成途径的Δ8,9-不饱和甾醇中间体的累积的试剂。 |
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| AbstractList | A method of promoting the generation of oligodendrocytes from oligodendrocyte precursor cells by enhancing their survival and/or maturation includes administering to the cell an effective amount of anagent that enhances and/or induces accumulation of delta8,9-unsaturated sterol intermediates of the cholesterol biosynthesis pathway in the oligodendrocyte precursor cells.
本申请涉及通过增强其存活和/或成熟促进少突胶质细胞从少突胶质细胞前体细胞产生的方法，包括向细胞给药有效量的增强和/或诱导少突胶质细胞前体细胞中胆固醇生物合成途径的Δ8,9-不饱和甾醇中间体的累积的试剂。 |
| Author | ELITT MATTHEW TESAR PAUL HUBLER ZITA ADAMS DREW ALLIMUTHU DHARMARAJA |
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| DocumentTitleAlternate | 促进髓鞘形成的化合物和方法 |
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| Title | COMPOUNDS AND METHODS OF PROMOTING MYELINATION |
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