Conversion recovery device of formic acid solvent in metronidazole production process

• Main Authors: WEI LIAN'AN, WEI MINGCHANG, CAI MIN, BAN ZHIHUA
• Format: Patent
• Language: Chinese; English
• Published: 21.05.2019
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention discloses a conversion recovery device of a formic acid solvent in a metronidazole production process and belongs to the technical field of disposal of wastewater containing formic acidin metronidazole production. The conversion recovery device consists of a reaction kettle, a condenser, a methanol storage device, a neutralization reaction kettle, a tail liquid storage tank and a methyl formate collection tank, wherein a process of esterifying formic acid and methanol, performing heating for reflux and conducting distillation to collect methyl formate is adopted. In order to solve a serious problem that the emission of industrial formic acid wastewater generated in a synthesis process of a bulk drug 2-methyl-5-nitroimidazole-1-ethanol exceeds the standards, the theoretical basis of conversion and recovery of the industrial formic acid wastewater is analyzed, correspondingly the industrial formic acid wastewater is converted into a methyl formate finished product with certain concentration and so