Cypress pollen allergen educt, immersion liquid thereof and preparation method of immersion liquid

• Main Authors: WEN LIPING, LI HONG, GUAN KAI, YIN JIA, MA WUQIANG, ZHOU JUNXIONG, WANG LIANGLU
• Format: Patent
• Language: Chinese; English
• Published: 21.05.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides a cypress pollen allergen educt, an immersion liquid thereof and a preparation method of the immersion liquid. The cypress pollen allergen educt contains an amino acid sequenceof cypress pollen allergen protein shown as SEQ ID NO.4-SEQ ID NO.7. The immersion liquid of the educt can be prepared by cypress pollen collection, drying, degreasing, extraction, ultrafiltration andconcentration, freeze drying, redissolving and other process methods. The cypress pollen allergen educt has the advantages of high specificity, complete extraction of allergenic cypress protein components, stable total biological potency, long validity period and good aseptic effect. The immersion liquid of the educt can be effectively used for skin pricking test diagnoses of allergic reaction diseases and can also be used for in-vitro basophil activation test diagnoses, intradermal test diagnoses and specific immunotherapy after proper dilution (10-2)-(10-20); the allergic reaction diseasesinduced by cypress pollen c