Screening of heparin sodium raw materials used for production of enoxaparin sodium

• Main Authors: LI LING, ZHENG HUIWU, DUAN CHENGKUN
• Format: Patent
• Language: Chinese; English
• Published: 12.04.2019
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; PHYSICS; TESTING

The invention relates to the technical field of heparin sodium, in particular to a screening of heparin sodium raw materials used for production of enoxaparin sodium. The screening of the heparin sodium raw materials used for production of the enoxaparin sodium screens the heparin sodium raw materials for producing the enoxaparin sodium by adopting a correlation coefficient method, and specifically comprises an enzymatic hydrolysis step of the heparin sodium, a separation and analysis step, and a calculating step of results. The screening of the heparin sodium raw materials used for productionof the enoxaparin sodium screens the heparin sodium raw materials for producing the enoxaparin sodium by adopting the correlation coefficient method. A correlation table and a correlation graph may reflect a correlation and a correlation direction thereof between two variables. The correlation coefficient is a statistical indicator to reflect a close degree of the correlation between the variables. The correlation coeffi