ANTI-EGFR ANTIBODY DRUG CONJUGATES

The invention relates to anti-Epidermal Growth Factor Receptor (EGFR) antibody drug conjugates (ADCs) which inhibit Bcl-xL, including compositions and methods of using said ADCs. 本发明涉及抑制Bcl-xL的抗表皮生长因子受体(EGFR)抗体药物偶联物(ADC)；包括使用所述ADC的组合物和方法。...

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Bibliographic Details
Main Authors BOGHAERT ERWIN R, SULLIVAN GERARD M, SOUERS ANDREW J, JUDD ANDREW A, TAO ZHI-FU, PHILLIPS ANDREW C, SONG XIAOHONG, DOHERTY GEORGE, FREY ROBIN R, BRUNCKO MILAN
Format Patent
LanguageChinese
English
Published 09.04.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to anti-Epidermal Growth Factor Receptor (EGFR) antibody drug conjugates (ADCs) which inhibit Bcl-xL, including compositions and methods of using said ADCs. 本发明涉及抑制Bcl-xL的抗表皮生长因子受体(EGFR)抗体药物偶联物(ADC)；包括使用所述ADC的组合物和方法。
Bibliography:Application Number: CN201780047927