Application of FLZ in preparations of neuroprotective drugs

• Main Authors: AN JUNYONG, JIA ZHENHUA, WU XIANGJUN, WANG CHAO, WU YILING
• Format: Patent
• Language: Chinese; English
• Published: 29.03.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention discloses an application of FLZ in preparations of neuroprotective drugs and belongs to the technical field of neuroprotective drugs. In the application of the FLZ in treating orpreventing cranial nerve injury drugs, pharmaceutically acceptable excipients are added into the FLZ to prepare clinically available drug dosage forms. Specifically, the FLZ is applied in preparations of drugs for treating and preventing nerve injury caused by cerebral hemorrhage, or applied in preparations of drugs for treating and preventing nerve injury caused by cerebral ischemia-reperfusion.Tests confirm that the FLZ has neuroprotective effects and can effectively treat or prevent the nerve injury caused by the cerebral ischemia-reperfusion, the nerve injury caused by the cerebral hemorrhage, and various nerve injuries of Guillian-Barre, etc. 芬乐胺在制备神经保护药物中的应用，属于神经保护药物的技术领域，芬乐胺在治疗或预防脑神经损伤药物中的应用，将芬乐胺加入药学上可接受的辅料制成临床可用的药物剂型。具体为芬乐胺在制备治疗或预防脑出血所致神经损伤药物中的应用，或芬乐胺在制备治疗或预防脑缺血再灌注所致神经损伤药物中的应用。试验证实，芬乐胺具有神经保护作用，并且可以有效治疗或者预