Composition comprising phosphodiesterase type 5 inhibitor for inhibiting apoptosis of nerve cells

• Main Authors: KIM MYUNG-HWA, KU SAE-KWANG, CHOUNG JAE-JUN
• Format: Patent
• Language: Chinese; English
• Published: 22.03.2019
• Subjects: FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES

The invention relates to the use of a composition comprising a phosphodiesterase type 5 active inhibitor for inhibiting apoptosis of cranial nerve cells. According to the invention, the phosphodiesterase type 5 inhibitor exhibits a protective effect on nerve cells by inhibiting apoptosis of cranial nerve cells. Thus, the invention can be effectively used to prevent, alleviate, and treat cranial nerve disease. 本发明涉及包含5型磷酸二酯酶活性抑制剂的脑神经细胞的细胞凋亡抑制用组合物的用途。根据本发明，5型磷酸二酯酶抑制剂抑制脑神经细胞的细胞凋亡，来呈现对神经细胞的保护作用。因此，本发明可有用地利用于脑神经疾病的预防、改善及治疗。