ANTI-TIM-3 ANTIBODIES AND METHODS OF USE THEREOF

The instant disclosure provides antibodies that specifically bind to TIM-3 (e.g., human TIM-3) and antagonize TIM-3 function. Also provided are pharmaceutical compositions comprising these antibodies,nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodi...

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Bibliographic Details
Main Authors WAIGHT JEREMY DALE, BREOUS-NYSTROM EKATERINA VLADIMIROVNA, WILSON NICHOLAS STUART, VAN DIJK MARC, UNDERWOOD DENNIS JOHN
Format Patent
LanguageChinese
English
Published 15.03.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The instant disclosure provides antibodies that specifically bind to TIM-3 (e.g., human TIM-3) and antagonize TIM-3 function. Also provided are pharmaceutical compositions comprising these antibodies,nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies. 本公开提供了与TIM-3(例如，人TIM-3)特异性结合并拮抗TIM-3功能的抗体。还提供了包含这些抗体的药物组合物，编码这些抗体的核酸，用于制备这些抗体的表达载体和宿主细胞，及使用这些抗体治疗受试者的方法。
Bibliography:Application Number: CN201780046441