Synthesizing method of 4,7-diphenyl-1,10-o-phenanthroline

• Main Author: LUO SHUPING
• Format: Patent
• Language: Chinese; English
• Published: 12.03.2019
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention provides a preparation method of 4,7-diphenyl-1,10-o-phenanthroline (I). The preparation method comprises the following steps of pumping a mixed acid solution of 3-chloropropiophenone (II) and o-phenylenediamine (III) into a micro-channel reactor, heating to certain reaction temperature, reacting for a period of time, cooling and filtering the reaction liquid flowing out, neutralizing filter cake by ammonia water, rinsing, and then filtering, so as to obtain the 4,7-diphenyl-1,10-o-phenanthroline. The preparation method has the advantages that by adopting the micro-channel reaction technology, the continuous production of 4,7-diphenyl-1,10-o-phenanthroline is realized; the safety and stability of the technology are high, the operation is simple, and the scale amplification and industrialized production are convenient. The structural formula of the 4,7-diphenyl-1,10-o-phenanthroline is shown in the description. 本发明提供种4,7-二苯基-1,10-邻菲咯啉(I)的制备方法：将3-氯苯丙酮(II)和邻苯二胺(III)的混酸溶液泵入微通道反应器，加热到定的反应温度下保留反应定时间后，