Preparation method of lilial intermediate p-tert-butyl-alpha-methylcinnamaldehyde

• Main Authors: ZHONG JUANJUAN, HUANG SHANSHAN, LIU BENGEN, ZHONG TIANMING, LI CONGCONG, LI YUXIANG, YU MING, FANG WANJUN, LEI HAIHONG, XIE KUN, MA XIAO
• Format: Patent
• Language: Chinese; English
• Published: 22.02.2019
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; METALLURGY; ORGANIC CHEMISTRY

The invention provides a preparation method of a lilial intermediate p-tert-butyl-alpha-methylcinnamaldehyde. The preparation method comprises the steps: charging, dropwise adding of propionaldehyde,heat preservation reaction, crystallization and aftertreatment. A p-tert-butyl-alpha-methylcinnamaldehyde crystal with the purity being larger than or equal to 99% is obtained, the content of p-tert-butyl-alpha-methylcinnamaldehyde at a middle position is lower than 0.1%, high-quality lilial containing larger than or equal to 99% of para-lilial can be obtained if p-tert-butyl-alpha-methylcinnamaldehyde is directly used for a hydrogenation reaction, and a crystallization mother liquid is used for recycling. The process provided by the invention has the advantages such as multiple recycle of a catalyst, simplicity in operation, low energy consumption, environment friendliness and good product quality. 本发明提供种铃兰醛中间体对叔丁基-α-甲基肉桂醛的制备方法，所述制备方法，包括加料、滴加丙醛、保温反应、结晶、后处理。得到纯度≥99%的对叔丁基-α-甲基肉桂醛晶体，其中间位叔丁基-α-甲基肉桂醛含量低于0.1%，直接用于加氢反应，