Transparent lipid emulsion

• Main Authors: TONG SHUWEN, ZHONG SHAOPENG, ZHOU LIYING, LU DI, LU XIAOYUN, YANG ZHENZHEN
• Format: Patent
• Language: Chinese; English
• Published: 22.01.2019
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses a transparent lipid emulsion composition. The lipid emulsion is a transparent or semitransparent solution, and contains an active pharmaceutical ingredient, lecithin, a non-aqueous carrier and a surfactant, specifically, 0.1-5.0 % of the active pharmaceutical ingredient, 0.1-5 % of the lecithin, 0.1-5.0 % of the non-aqueous carrier, and 0.1-10.0 % of the surfactant. The emulsion has the excellent stability and can be stored for a long term, the lipid emulsion is the homogeneous, single-phase, and transparent or semitransparent emulsion, the transparency detection can becarried out, the change of the emulsion can be effectively observed, and the medication safety of patients can be improved. 本发明公开了种透明的脂质乳剂组合物，本发明的脂质乳剂是种透明或半透明的溶液，其含有药物活性成分，卵磷脂，非水载体及表面活性剂，其中含有0.1%-5.0%药物活性成分，0.1%~5%卵磷脂，0.1%-5.0%非水载体及0.1%-10.0%表面活性剂。本发明的乳剂具有优异的稳定性，可长期储存，本发明的脂质乳剂为均、单相、透明或半透明的乳剂，可进行透明度检测，能有效的观察到乳剂的变化，提高了患者的用药安全。