New use of pyrrole derivatives

The invention discloses a novel use of pyrrole derivatives. The structure of the pyrrole derivative is represented by a general formula (I). The pyrrole derivatives are first found to be effective ininhibiting tyrosinase activity, are used for tyrosinase inhibitor and treatment of pigmentation, pigm...

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Bibliographic Details
Main Authors LYU HUI, LI DONGLI, XU XUETAO, HUANG DANYING, ZHANG KUN
Format Patent
LanguageChinese
English
Published 11.01.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Summary:The invention discloses a novel use of pyrrole derivatives. The structure of the pyrrole derivative is represented by a general formula (I). The pyrrole derivatives are first found to be effective ininhibiting tyrosinase activity, are used for tyrosinase inhibitor and treatment of pigmentation, pigmentation, vitiligo drugs, and have the advantages of convenient use, small toxic and side effects,lower dosage. 本发明公开了种吡咯衍生物的新用途，所述吡咯衍生物结构通式如式(Ⅰ)所示：本申请首次发现所述吡咯衍生物可有效抑制酪氨酸酶活性，用于酪氨酸酶抑制剂和治疗色素沉着、色斑、白癜风的药物，具有使用方便、毒副作用小、使用剂量低的优点。
Bibliography:Application Number: CN201811103498