CRISPR/CAS systems for C-1 fixing bacteria

The invention provides methods of genetically engineering a C1-fixing bacterium using a clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) (CRISPR/Cas) system.Preferably, the Cas protein is under the control of an inducible promoter. 本发明提供了种使用规律成簇间隔短回文重复序列(CRI...

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Bibliographic Details
Main Authors NAGARAJU SHILPA, KOEPKE MICHAEL
Format Patent
LanguageChinese
English
Published 21.12.2018
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The invention provides methods of genetically engineering a C1-fixing bacterium using a clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) (CRISPR/Cas) system.Preferably, the Cas protein is under the control of an inducible promoter. 本发明提供了种使用规律成簇间隔短回文重复序列(CRISPR)/CRISPR相关(Cas)(CRISPR/Cas)系统对C1固定菌进行基因工程改造的方法。优选地，Cas蛋白处于诱导型启动子的控制之下。
Bibliography:Application Number: CN201780021744