Preparation method of hydrophilic coating on guide wire surface of medical catheter, and product of preparation method

• Main Authors: XU FUJIAN, YANG MEIPING, DUAN SHUN, DING XUEJIA
• Format: Patent
• Language: Chinese; English
• Published: 21.12.2018
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL

The invention discloses a preparation method of a hydrophilic coating on a guide wire surface of a medical catheter, and the product of the preparation method. The method comprises the following steps: dissolving aqueous dispersion of resin and hydrophilic polymer(s) in water, mixing and stirring to obtain a uniform solution; adjusting the pH value of the solution, adding crosslinking agent(s), stirring uniformly, and carrying out ultrasonic treatment; immersing a guide wire of the medical catheter into the obtained solution, pulling, curing and drying to form a film; the resin is water-basedamino resin, water-based acrylic resin, water-based epoxy resin, waterborne polyurethane or derivatives thereof; the hydrophilic polymer(s) is/are one or more of polyvinylpyrrolidone, polyvinyl alcohol, xanthan gum, agarose and sodium alginate; the crosslinking agent(s) is/are one or two of a siloxane crosslinking agent, an epoxy crosslinking agent, an aziridine crosslinking agent, a carbodiimidecrosslinking agent and a p