Integrated microfluidic device for serial fluidic operations, and method of performing serial fluidic operations

• Main Authors: SPENCER DANIEL CHRISTOPHER, DOTHIE PAMELA ANN
• Format: Patent
• Language: Chinese; English
• Published: 30.11.2018
• Subjects: ACTUATING-FLOATS; ACYCLIC OR CARBOCYCLIC COMPOUNDS; BLASTING; CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE; CHEMISTRY; COCKS; DEVICES FOR VENTING OR AERATING; ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVEFUNCTIONING OF MACHINES OR INSTALLATIONS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; HEATING; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; LIGHTING; MEASURING; MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUIDLEVEL; MECHANICAL ENGINEERING; METALLURGY; METERING BY VOLUME; ORGANIC CHEMISTRY; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; PHYSICS; TAPS; TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION; TECHNICAL SUBJECTS COVERED BY FORMER USPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TESTING; THERMAL INSULATION IN GENERAL; TRANSPORTING; VALVES; WEAPONS

An integrated microfluidic device for carrying out a series of fluidic operations includes a housing (18) including a plurality of n microfluidic conduits, wherein n is at least three (20, 22, 24), and a rotating valve (10) having an internal channel (12) with an entrance port and an exit port that are angularly separated. The rotating valve is positionable in a first position to connect two of the n fluidic conduits (20, 22) via the internal channel, and upon rotating the valve to a second position, two other of the n fluidic conduits (22, 24) are connected by the internal channel. The devicefurther may include one or more fluidic chambers (44, 46) in fluid communication with respective fluidic conduits. Fluid contained in one fluidic chamber is transferrable by application of positive or negative gas pressure through associated fluidic conduits into another fluidic chamber via the internal channel. The device may be utilized to perform a variety of fluidic operations. 种用于执行系列流操作的集成微流设备，包括：外壳(18)，外壳(18)包括数量为