Application of 6-chloro-5-nitro-2,4-diaminopyrimidine in drug for treating chronic granulocytic leukemia

• Main Authors: SHI KAIQI, TANG YONGHONG, LIANG CHENGYUAN, TIAN DANNI, XIA JUAN, CHANG MINGHUI, WANG XUECHUAN, LI HAN
• Format: Patent
• Language: Chinese; English
• Published: 30.11.2018
• Subjects: APPARATUS THEREFOR; CHEMISTRY; GENERAL METHODS OF ORGANIC CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses application of 6-chloro-5-nitro-2,4-diaminopyrimidine in a drug for treating chronic granulocytic leukemia. A synthesis method for the 6-chloro-5-nitro-2,4-diaminopyrimidine ischaracterized in that a target compound is prepared by reacting guanidine hydrochloride, amino formy...