Colorimetric and fluorescent probe capable of rapidly detecting phosgene and synthetic method of colorimetric and fluorescent probe

• Main Authors: SONG QINHUA, WANG SHAOLIN
• Format: Patent
• Language: Chinese; English
• Published: 09.11.2018
• Subjects: ADHESIVES; CHEMISTRY; DYES; HETEROCYCLIC COMPOUNDS; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE; MEASURING; METALLURGY; MISCELLANEOUS APPLICATIONS OF MATERIALS; MISCELLANEOUS COMPOSITIONS; NATURAL RESINS; ORGANIC CHEMISTRY; PAINTS; PHYSICS; POLISHES; TESTING

The invention discloses a colorimetric and fluorescent probe capable of rapidly detecting phosgene and a synthetic method of the colorimetric and fluorescent probe. The colorimetric and fluorescent probe is characterized by being a compound 2'-aminomethyl-3',3'-dimethylpyrrolo[3,4]N-butyl-1,8-naphthalimide, wherein 1,8-naphthalimide is taken as a fluorophore, and 2'-aminomethyl-3,3'-dimethylpyrrole is taken as a reaction site of phosgene. The synthetic method comprises two times of ''one-pot reactions'', namely, oxidation/reduction reaction and methyl sulfonylation/nucleophilic substitution/reduction reaction. Compared with the prior art for detecting phosgene, by utilizing colorimetric and fluorescent response characteristics of a probe Phos-3 to the specificity of phosgene, the colorimetric and fluorescent detection of phosgene can be realized, and the colorimetric and fluorescent probe is high in response speed, low in detection limit and high in selectivity; and real-time visual detection of phosgene in a