METHOD OF PHOTODYNAMIC THERAPY (PDT) FOR BLADDER CANCER

This invention relates to a method of photodynamic therapy (PDT) for bladder cancer and its use as an adjuvant or neoadjuvant therapy in the treatment of bladder cancer. The invention provides a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a...

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Bibliographic Details
Main Authors GODAL ASLAK, HESTDAL KJETIL
Format Patent
LanguageChinese
English
Published 23.10.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to a method of photodynamic therapy (PDT) for bladder cancer and its use as an adjuvant or neoadjuvant therapy in the treatment of bladder cancer. The invention provides a composition comprising hexyl 5-ALA ester (HAL) or a pharmaceutically acceptable salt thereof for use in a method of photodynamic therapy for bladder cancer, wherein said composition is instilled into the bladder of a patient in need of such treatment and the inside of said bladder is exposed to blue light having a fluence rate of 1.5 to 12.5 mW/cm2 本发明涉及用于膀胱癌的光动力疗法(PDT)的方法及其作为辅助或新辅助疗法在膀胱癌治疗中的用途。本发明提供种用于膀胱癌的光动力疗法的方法的包括5-ALA己酯(HAL)或其药学上可接受的盐的组合物，其中所述组合物被滴注入需要这种治疗的患者的膀胱中，并且将所述膀胱内部暴露于具有1.5至12.5mW/cm2的能流率的蓝光。
Bibliography:Application Number: CN201680079638