Chitosan superfine fiber systems

• Main Authors: MCCARTHY SIMON, CLARE BRIAN, DVORAK RADIM, MACHAT JIRI
• Format: Patent
• Language: Chinese; English
• Published: 28.09.2018
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOSITIONS BASED THEREON; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; WORKING-UP

The present chitosan-based superfine fiber invention relates to compositions, formulations, and processes that result in numerous significant advantages for the production and use of superfine fiber bioactive matrices in biomedical applications. The present invention relates to superfine, chitosan-based fibers, wherein the chitosan-based fibers have a percentage chitosan content of at least about20% w/w, and highly conformable and compliant matrices comprising such fibers, processes for their production, and related formulations. The superfine chitosan-based fibers of the invention preferablyinclude microfibers with diameter less than or equal to about 10 microns and micron and submicron fibers that are about 2 microns and less. 基于壳聚糖的超细纤维的本发明涉及组合物、制剂和方法，其导致对于超细纤维生物活性基质的生产和在生物医学应用中的用途而言众多显著优点。本发明涉及超细的基于壳聚糖的纤维，其中所述基于壳聚糖的纤维具有至少约20％w/w的壳聚糖含量百分比和高度适合的且顺从的包含这样的纤维的基质，它们的生产方法，和有关的制剂。本发明的超细的基于壳聚糖的纤维优选地包括具有小于或等于约10微米的直径的微纤维、以及约2微米和更小的微米和亚微米纤维。