METHODS FOR INHIBITING CONVERSION OF CARNITINE TO TRIMETHYLAMINE (TMA)

The invention provides a method of inhibiting the conversion of carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositionscomprising a compound set forth in Formula (I) wherein the compound is administered in an amount eff...

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Bibliographic Details
Main Authors WOS JOHN AUGUST, STANTON DAVID THOMAS, DEUTSCH ANGELA JANE, REILLY MICHAEL, CODY DAVID BLAIR, GARCIA-GARCIA JOSE CARLOS, GERBERICK GEORGE FRANKLIN, INGLIN THOMAS ALFRED, REED JODIE MICHELLE, HAZEN STANLEY LEON
Format Patent
LanguageChinese
English
Published 28.09.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention provides a method of inhibiting the conversion of carnitine to trimethylamine (TMA) and lowering TMAO in an individual comprising administering to the individual one or more compositionscomprising a compound set forth in Formula (I) wherein the compound is administered in an amount effective to inhibit conversion of carnitine to TMA in the individual. 本发明提供抑制个体中肉毒碱向三甲胺(TMA)转化并降低TMAO的方法，该方法包括将种或多种包含式(I)所示化合物的组合物施用给个体：其中化合物以有效抑制个体中肉毒碱向TMA转化的量施用。
Bibliography:Application Number: CN201680070816