Flavonoid glycoside compound as well as preparation method and application thereof

The invention provides a flavonoid glycoside compound as well as a preparation method and application thereof. The flavonoid glycoside compound has a structure shown in formula I, can obviously reducethe content of LDH and MDA in brain tissues and improve the content of SOD, and has a good protectiv...

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Bibliographic Details
Main Authors ZHAO YIWU, SONG YALING, XIAO WEI, LUO XIN, XIE XUE, WANG XUEJING, WANG ZHENZHONG, LIU LINA
Format Patent
LanguageChinese
English
Published 14.09.2018
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:The invention provides a flavonoid glycoside compound as well as a preparation method and application thereof. The flavonoid glycoside compound has a structure shown in formula I, can obviously reducethe content of LDH and MDA in brain tissues and improve the content of SOD, and has a good protective effect on cerebral ischemia reperfusion injuries of rats. At the same time, the compound can inhibit the growth of tumor cells and has certain anti-tumor activity. 本发明提供了种黄酮苷类化合物及其制备方法和应用，所述黄酮苷类化合物具有式Ⅰ所示结构，该化合物能显著降低脑组织内LDH和MDA含量，并提高SOD含量，对大鼠脑缺血再灌注损伤具有较好的保护作用。同时该化合物能抑制肿瘤细胞生长，具有定的抗肿瘤活性。
Bibliography:Application Number: CN201710120617