Method for SERS quantitative analysis by using self-assembled three-dimensional nanostructure as substrate

• Main Authors: ZHANG YUN, TIAN XIANGDONG, LIU SIYING, WU SIRONG
• Format: Patent
• Language: Chinese; English
• Published: 17.08.2018
• Subjects: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MEASURING; NANOTECHNOLOGY; PERFORMING OPERATIONS; PHYSICS; SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; TESTING; TRANSPORTING

The invention discloses a method for SERS quantitative analysis by using a self-assembled three-dimensional nanostructure as a substrate. The method comprises the following steps: making precious metal nanoparticles form a nanoparticle monolayer film on a gas-liquid interface in an interface-assisted assembling manner; transferring the nanoparticle monolayer film to the substrate in a pulling manner to obtain a monolayer substrate; performing self-assembling on the substrate in a pulling manner after the monolayer substrate is dry, and repeating above steps until the substrate with a requirednumber of the nanoparticle layers is obtained; and immersing and adsorbing a sample to be detected in the obtained substrate, taking out the substrate a certain time later, drying the substrate, and performing SERS quantitative detection. The method has the advantages of simplicity, rapidness, low cost, high sensitivity, and accurate and reliable result. 本发明公开了种用自组装三维纳米结构为基底进行SERS定量分析的方法，该方法的步骤为：将贵金属纳米粒子通过界面辅助的组装方式在气液界面上形