QUICK DISSOLVING DIPHENHYDRAMINE ORAL DOSAGE FORM

An oral dosage form to deliver diphenhydramine through the sublingual or buccal mucosa. The oral dosage form can contain diphenhydramine, or a pharmaceutically acceptable salt thereof, a permeabilityenhancer, and a buffering agent. The buffering agent can achieve a pH of about 7.0 to about 8.0. The...

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Bibliographic Details
Main Authors SWIGART ERIN NICOLE, TRABOULSI ASHRAF, DANSEREAU RICHARD JOHN, LASTER BRIAN
Format Patent
LanguageChinese
English
Published 03.08.2018
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:An oral dosage form to deliver diphenhydramine through the sublingual or buccal mucosa. The oral dosage form can contain diphenhydramine, or a pharmaceutically acceptable salt thereof, a permeabilityenhancer, and a buffering agent. The buffering agent can achieve a pH of about 7.0 to about 8.0. The diphenhydramine can completely dissolve within about 2 minutes. 本发明提供了种通过舌下或颊面黏膜递送苯海拉明的口服剂型。所述口服剂型可包含苯海拉明、或其药学上可接受的盐、渗透增强剂和缓冲剂。所述缓冲剂可达到约7.0至约8.0的pH。苯海拉明可在约2分钟内完全溶解。
Bibliography:Application Number: CN201680074512