Promoters from corynebacterium glutamicum

Provided are native promoters comprising polynucleotides isolated from Corynebacterium glutamicum, and mutant promoters derived therefrom, which may be used to regulate, i.e., either increase or decrease, gene expression. Also provided are promoter ladders comprising a plurality of the promoters hav...

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Bibliographic Details
Main Authors MANCHESTER SHAWN P, GORA KATHERINE G, SERBER ZACH
Format Patent
LanguageChinese
English
Published 31.07.2018
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Provided are native promoters comprising polynucleotides isolated from Corynebacterium glutamicum, and mutant promoters derived therefrom, which may be used to regulate, i.e., either increase or decrease, gene expression. Also provided are promoter ladders comprising a plurality of the promoters having incrementally increasing promoter activity. Also provided are host cells and recombinant vectorscomprising the promoters, and methods of expressing genes of interest and producing biomolecules using the host cells. 提供了包含分离自谷氨酸棒杆菌的多核苷酸的天然启动子，及源于其的突变启动子，所述启动子可用于调节，即增加或减少基因表达。还提供了包含多个具有递增启动子活性的启动子的启动子梯。还提供了包含所述启动子的宿主细胞和重组载体，及使用所述宿主细胞表达目标基因并产生生物分子的方法。
Bibliography:Application Number: CN2016863286