Preparation method of dual-ion collaboration crosslinking rapid self-healing type bacteriostasis hydrogel

• Main Authors: WANG SHUXUE, CHI HONGJIN, LI QIURONG, FENG SHUANGJIANG, LYU YUANFEI
• Format: Patent
• Language: Chinese; English
• Published: 31.07.2018
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; GENERAL PROCESSES OF COMPOUNDING; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; WORKING-UP

Disclosed is dual-ion collaboration crosslinking rapid self-healing type bacteriostasis hydrogel. The hydrogel is generated by chemical and physical crosslinking of polyvinyl alcohol and agar, the internal structure is a three-dimensional network structure, and metal ion of the network structure are combinations of two of Fe3+, Al3+, Zn2+, Ca2+ and Cu2+; a preparation method of the bacteriostasishydrogel comprises the steps that agar and polyvinyl alcohol are dissolved into deionized water under the temperature of 95 DEG C, and then, acrylic acid is added into the mixture; nitrogen is introduced into the mixture for deoxygenation for 10 min, persulfate, N,N-methylene bisacrylamide and inorganic metal salt are added, the obtained solution is injected into a cylindrical model and kept at the temperature of 60-90 DEG C, the temperature is kept constant for 6-10 h, cooling is performed to reach the temperature of 2-5 DEG C, the temperature is kept constant for 1-5 h, the mixture is frozenat the temperature of sub