Yeast strains for the expression and secretion of heterologous proteins at high temperatures

• Main Authors: SKINNER RYAN, ARGYROS AARON, RICE CHARLES F, BARRETT TRISHA
• Format: Patent
• Language: Chinese; English
• Published: 17.07.2018
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The present disclosure relates to recombinant yeast strains capable of maintaining their robustness at high temperature as well as recombinant proteins expressed therefrom. The present disclosure alsoprovides methods for using the recombinant yeast strain for making a fermentation product. The present disclosure further process a process for making recombinant yeast strains capable of maintainingtheir robustness at high temperature. 本公开涉及能够维持在高温下的稳健性的重组酵母菌株以及由所述重组酵母菌株表达的重组蛋白。本公开还提供使用所述重组酵母菌株制备发酵产物的方法。本公开进步提供种用于制备能够维持在高温下的稳健性的重组酵母菌株的方法。