PD-1 binding proteins and methods of use thereof

• Main Authors: MORRISON LISA, HARIHARAN KANDASAMY, SUN JEONG-HOON, CHAN HENRY H, KEHRY MARILYN, LEUNG MONICA, TORRES SANAA, BENNETT BRYDON, JACKSON PILGRIM, CHAMBERLAIN PHILIP PAUL, KHATTRI ROLI
• Format: Patent
• Language: Chinese; English
• Published: 17.07.2018
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Provided herein are compositions, methods and uses involving antibodies that specifically bind to Programmed Death-1 (PD-1) and modulate the expression and/or activity of PD-1. 本文提供涉及特异性结合程序化死亡-1(PD-1)以及调节PD-1的表达和/或活性的抗体的组合物、方法和用途。