Preparation and application of thermally reversible Diels-Alder reaction based polymer-nanometer molybdenum disulfide sheet composite hydrogel

• Main Authors: YANG WENJING, ZHANG QI, WANG LIANHUI, YUWEN LIHUI, CHEN SIMOU
• Format: Patent
• Language: Chinese; English
• Published: 29.06.2018
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS; MEASURING; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; PHYSICS; TESTING; THEIR PREPARATION OR CHEMICAL WORKING-UP; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS

The invention belongs to the technical field of polymer biomedical materials and provides preparation and application of a thermally reversible Diels-Alder reaction based polymer-nanometer molybdenumdisulfide sheet composite hydrogel. The composite hydrogel is formed by performing thermally reversible Diels-Alder reaction in a nanometer thin-layer molybdenum disulfide sheet aqueous solution. Thethermally reversible Diels-Alder reaction is generated by maleimide groups in thiol-polyethylene glycol-maleimide and furan groups in furan hyaluronic acid under heat environment. The self-healing ability is that a material utilizes the photo-thermal transformation characteristic of a nanometer thin-layer molybdenum disulfide sheet under illumination of near infrared light to enable the temperature of hydrogel raise to a thermally reversible temperature of the Diels-Alder reaction, and thus the purpose of self healing is realized. According to the application, the nanometer two-dimensional material molybdenum disulfide