Preparation method of nanometer zinc-loaded hydroxyapatite

• Main Authors: ZHAO HONG, ZHAO YUN, YANG WEI, LIU MANGMANG, ZHAO BINYUAN
• Format: Patent
• Language: Chinese; English
• Published: 22.06.2018
• Subjects: CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; COMPOUNDS THEREOF; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HUMAN NECESSITIES; HYGIENE; INORGANIC CHEMISTRY; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; NON-METALLIC ELEMENTS

The invention discloses a preparation method of nanometer zinc-loaded hydroxyapatite. The preparation method takes calcium salt and a phosphate solution as raw materials and a zinc agent as an additive, the zinc ion is loaded on the nanometer hydroxyapatite, the content of zinc in a product is 5%, the calcium salt and the phosphate solution are weighed proportionally at the specific ratio of the calcium atom to the phosphorus atom of 1.62-1.72, moreover, the zinc agent is added, the mixture is heated and reacted at the constant temperature in a water bath, and the reaction temperature is controlled to 70 DEG C to 100 DEG C to prepare the nanometer zinc-loaded hydroxyapatite. The preparation process is simple, the operability is strong, due to the low-temperature reaction condition, the preparation cost is reduced greatly, and the prepared nanometer zinc-loaded hydroxyapatite has an excellent medical effect. 本发明公开了种纳米载锌羟基磷灰石的制备方法，以钙盐和磷酸盐溶液为原料，以锌试剂作为添加剂，将锌离子负载到纳米级羟基磷灰石上，其中产物锌含量为5％，具体的按照1.67±0.05钙磷原子比例称取钙盐和磷酸盐溶液