Method for extracting and separating coenzyme Q10 by ionic liquid

• Main Authors: ZHANG ZHIGUO, BAO ZONGBI, REN QILONG, LI MIN, XING HUABIN, YANG QIWEI, YANG YIWEN
• Format: Patent
• Language: Chinese; English
• Published: 18.05.2018
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION ORPROCESSING OF GOODS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; METALLURGY; ORGANIC CHEMISTRY; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS; TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINSTCLIMATE CHANGE

The invention discloses a method for extracting and separating coenzyme Q10 by using ionic liquid. The coenzyme Q10 with high purity is obtained from an extraction solution with a fractionation extraction technology on the basis of a crude extract of coenzyme Q10 as a raw material, a nonpolar organic solvent as a raw material solvent and a detergent and the ionic liquid or a binary mixed solvent containing the ionic liquid and a polar organic solvent as an extractant. The ionic liquid extractant used in the method has better thermal stability and higher selectivity than traditional organic solvents, and the whole process is simple and reliable, the product purity is high, and the yield is high, so that the method is suitable for industrial production. 本发明公开了种采用离子液体萃取分离辅酶Q10的方法，以辅酶Q10粗提物为原料，以非极性有机溶剂为原料溶剂和洗涤剂，以离子液体或者离子液体-极性有机溶剂组成的二元混合溶剂为萃取剂，采用分馏萃取技术从萃余液中得到高纯度的辅酶Q10。该方法所采用的离子液体萃取剂比传统有机溶剂具有更好的热稳定性和更高的选择性，整个工艺简单可靠、产品纯度高、收率高，适合工业化生产。