METHOD

• Main Author: HOGSET ANDERS
• Format: Patent
• Language: Chinese; English
• Published: 27.03.2018
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

The invention concerns a method of generating an immune response in a subject, comprising administering to the subject an antigenic molecule, a photosensitizing agent, a checkpoint inhibitor, and irradiating said subject with light of a wavelength effective to activate the photosensitizing agent to generate an immune response. Preferably the method is a method of vaccination. The invention also provides related methods, compositions, cells, uses, products and kits. 本发明涉及种在受试者中引起免疫反应的方法，包括向所述受试者施用抗原分子、光敏剂、检查点抑制剂，并且用有效激活所述光敏剂的波长的光辐照所述受试者以引起免疫反应。优选地，所述方法是种疫苗接种方法。本发明还提供相关的方法、组合物、细胞、用途、产品和试剂盒。