Purpose of walnut shell flavone extract in preparation of medicine for treating hyperlipidemia

• Main Authors: CHEN CHAOYIN, YANG YINGNING, LIU JINGYUAN, LUO YAN, ZHAO SHENGLAN
• Format: Patent
• Language: Chinese; English
• Published: 27.03.2018
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention discloses a purpose of a walnut shell flavone extract in preparation of a medicine for treating hyperlipidemia. The walnut shell flavone extract is an ethanol extract of walnut shell, and general flavone content in the extract is no less than 3%. According to the invention, hyperlipidemia means that total cholesterol, triglyceride, and low-density lipoprotein cholesterol content in serum and liver are increased, and high-density lipoprotein cholesterol content is reduced. The experiment result shows that the walnut shell flavone extract can obviously inhibit body weight increaseof rats with high-fat diet, Lee's index and fat index can be reduced, a lipid level in serum and liver is obviously reduced, such as reduction of TC, TG and LDL-C as well as increase of HDL-C, the walnut shell flavone extract has obvious protection effect and is capable of improving liver damage and liver fatty degeneration, and has effects for preventing and treating hyperlipidemia. 本发明公开了种核桃壳黄酮提取物及其在制备治疗高脂血症药物中的用途。所述核桃壳