Agent release rate-adjustable calcium carbonate/calcium alginate composite microsphere and its preparation method based on bi-aqueous biomineralization technology

The invention discloses an agent release rate-adjustable calcium carbonate/calcium alginate composite microsphere and its preparation method based on a bi-aqueous biomineralization technology and belongs to the field of polymers and agent controlled release carriers. The preparation method has simpl...

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Bibliographic Details
Main Authors XIE CHUNYAN, MENG SHIXIN, SONG XUANYI, MENG TAO, GUO TING
Format Patent
LanguageChinese
English
Published 13.03.2018
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Summary:The invention discloses an agent release rate-adjustable calcium carbonate/calcium alginate composite microsphere and its preparation method based on a bi-aqueous biomineralization technology and belongs to the field of polymers and agent controlled release carriers. The preparation method has simple processes, is easy to operate and has low energy consumption. The system is mild and non-toxic. Through the selective distribution characteristics of the bi-aqueous relative macromolecular proteins, the macromolecular protein agents can be well retained in the inner phase of a bi-aqueous droplet template. In curing, the macromolecular protein agents can be well encapsulated in composite calcium alginate microspheres. The preparation method has an excellent encapsulation rate. Through adjustinga urease concentration of the system, calcium carbonate/calcium alginate composite microspheres with different compounding degrees are prepared and a release rate of an agent encapsulated in the microspheres can be controlle
Bibliography:Application Number: CN201710768009