Polymerase Variants And Uses Thereof

Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227, I295, Y342, T343, I357, S360, L361, I363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, Q546, A547, L549, I550, N552, G553, F558, A596, G...

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Bibliographic Details
Main Authors AYER ARUNA, SHULTZ TYLER, ARNOLD CLEOMA, LEDERMAN ILYA, SCHWAB CHARLES, THAI EILEEN, MCGAW COLIN
Format Patent
LanguageChinese
English
Published 26.01.2018
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:Described herein is a variant pol6 polymerase having at least one mutation selected from H223, N224, Y225, H227, I295, Y342, T343, I357, S360, L361, I363, S365, S366, Y367, P368, D417, E475, Y476, F478, K518, H527, T529, M531, N535, G539, P542, N545, Q546, A547, L549, I550, N552, G553, F558, A596, G603, A610, V615, Y622, C623, D624, I628, Y629, R632, N635, M641, A643, I644, T647, I648, T651, I652,K655, W656, D657, V658, H660, F662, L690 and combinations thereof. 本文描述了具有至少个选自以下的突变的变体pol6聚合酶：H223、N224、Y225、H227、I295、Y342、T343、I357、S360、L361、I363、S365、S366、Y367、P368、D417、E475、Y476、F478、K518、H527、T529、M531、N535、G539、P542、N545、Q546、A547、L549、I550、N552、G553、F558、A596、G603、A610、V615、Y622、C623、D624、I628、Y629、R632、N635、M641、A643、I644、T647、I648、T651、I652、K655、W656、D657、V658、H660、F662、L690及其组合。
Bibliography:Application Number: CN201680027667