Whole blood based mRNA markers for predicting prostate cancer and methods of detecting the same

• Main Authors: RICCI DEBORAH, THOMAS SHIBU, RAJPUROHIT YASHODA, SCHAFFER MICHAEL, GORMLEY MICHAEL
• Format: Patent
• Language: Chinese; English
• Published: 09.01.2018
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; ENZYMOLOGY; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; METALLURGY; MICROBIOLOGY; MUTATION OR GENETIC ENGINEERING; PROCESSES OF PREPARING SUCH COMPOSITIONS; SPIRITS; VINEGAR; WINE

Provided are whole blood based mRNA biomarkers for predicting prostate cancer and methods of detecting the same. The disclosed mRNA markers and methods enable the identification/diagnosis of a patientwith prostate cancer, identification of a patient with/prediction of high-risk prostate cancer, and treatment of a patient with prostate cancer. Also provided are gene chips comprising the disclosedwhole blood based mRNA biomarkers. 本发明提供了用于预测前列腺癌的基于全血的mRNA生物标记和检测该mRNA生物标记的方法。本发明所公开的mRNA标记物和方法允许辨别/诊断患有前列腺癌的患者，辨别患有/预测患有高危前列腺癌患者，以及治疗患有前列腺癌的患者。本发明还提供了包含本发明所公开的基于全血的mRNA生物标记的基因芯片。