Fluorescent molecular probe with DPP as fluorescent core and capable of selectively and reversibly recognizing fluorine ion

• Main Authors: YANG XIAOFENG, LIANG SHUAI, ZHANG YAN, CUI YU, HAN JIXUN, ZHANG HAO, SUN GUOXIN
• Format: Patent
• Language: Chinese; English
• Published: 09.01.2018
• Subjects: ADHESIVES; CHEMISTRY; DYES; HETEROCYCLIC COMPOUNDS; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FORELSEWHERE; MEASURING; METALLURGY; MISCELLANEOUS APPLICATIONS OF MATERIALS; MISCELLANEOUS COMPOSITIONS; NATURAL RESINS; ORGANIC CHEMISTRY; PAINTS; PHYSICS; POLISHES; TESTING

The invention discloses a colorimetric fluorescent small molecule probe for fluorine ion detection, which has the advantages of capability of naked eye observation, reversibility, high selectivity andhigh sensitivity. The probe disclosed by the invention has the beneficial effects of simple probe molecule synthesis, high fluorine ion detection selectivity and good sensitivity, and can detect a fluorine ion reversibly in the presence of HSO4, and can be reused. The probe has high fluorescence intensity and is orange-red, and when the fluorine ion is added, the fluorescence is quenched and thecolor changes to a purple-black color, and the significant change in color can be observed by naked eyes. The probe quickly responds to the fluorine ion and completes the response immediately after adding the fluorine ion, and the detection limit is as low as 10nM. 本发明公开了种可以裸眼观察的可逆的高选择性高灵敏度的检测氟离子的比色型的荧光小分子探针。本发明的有益效果在于，该探针分子合成简单，检测氟离子选择性高，灵敏度好，在HSO的存在下可以可逆的检测氟离子，且该探针可以重复利用。该探针本身荧光强度高，呈橙红色，加入氟离子之后荧光淬灭，颜色变为紫黑色，裸眼可见颜色的明显变化。该探