Method for preparing cellulose dihydropyrimidinone derivative on basis of multi-component click chemistry

• Main Authors: WANG BIJIA, ZHU ZUMEI, LIU HONGCHEN, XU HONG, ZHONG YI, MAO ZHIPING, ZHANG LINPING, RONG LIDUO, SUI XIAOFENG
• Format: Patent
• Language: Chinese; English
• Published: 22.12.2017
• Subjects: CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES THEREOF; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; THEIR PREPARATION OR CHEMICAL WORKING-UP

The invention relates to a method for preparing a cellulose dihydropyrimidinone derivative on the basis of multi-component click chemistry. The method comprises steps as follows: cellulose acetoacetate is added to a solvent to be dissolved uniformly, and a cellulose acetoacetate solution is obtained; aldehydes, ureas and metal chloride salts are added to the solvent to be dissolved uniformly, a mixed solution is obtained and dropwise added to the cellulose acetoacetate solution, thermostatic reaction is performed, an obtained solution is cooled to the room temperature, precipitates are separated out in ice water, washed, purified and subjected to vacuum drying, and the cellulose dihydropyrimidinone derivative is obtained. According to the method, reaction substrates are cheap and abundant, the reaction is fast, efficient, green and economical, and the preparation process is simple and safe and suitable for large-scale production; the cellulose dihydropyrimidinone derivative prepared with the method has good b