Methods for the regeneration of articular cartilage in vivo

A pharmaceutical composition is provided that is useful to enhance the repair of articular cartilage, to treat a joint injury or to prevent, inhibit or treat osteoarthritis in a mammal. The composition may include an effective amount of an isolated protein that is a chemoattractant for chondrogenic...

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Bibliographic Details
Main Authors SEOL DONG RIM, SALEM ALIASGER K, MARTIN JAMES A, BROUILLETTE MARC, YU YIN, DO ANH-VU T, SOURKOHI BEHNOUSH KHORSAND
Format Patent
LanguageChinese
English
Published 28.11.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A pharmaceutical composition is provided that is useful to enhance the repair of articular cartilage, to treat a joint injury or to prevent, inhibit or treat osteoarthritis in a mammal. The composition may include an effective amount of an isolated protein that is a chemoattractant for chondrogenic progenitor cells and/or an effective amount of an isolated protein that is a chondrogenic factor or a nucleic acid sequence that encodes a chondrogenic factor. 提供可用于在哺乳动物中增强关节软骨修复、治疗关节损伤或预防、抑制或治疗骨关节炎的药物组合物。该组合物可包括有效量的作为软骨形成祖细胞的化学引诱物的分离的蛋白质和/或有效量的作为软骨形成因子的分离的蛋白质或编码软骨形成因子的核酸序列。
Bibliography:Application Number: CN201680014723