Targeted gas-filled microvesicles formulation
Suspension of gas-filled microvesicles comprising a targeting ligand for binding to KDR or VEGF/KDR complex. The suspension is obtained by reconstituting a freeze-dried residue with a carbohydrate-containing solution in the presence of a physiologically acceptable gas and is stabilized by the presen...
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Main Authors | , |
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Format | Patent |
Language | Chinese English |
Published |
26.09.2017
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Subjects | |
Online Access | Get full text |
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Summary: | Suspension of gas-filled microvesicles comprising a targeting ligand for binding to KDR or VEGF/KDR complex. The suspension is obtained by reconstituting a freeze-dried residue with a carbohydrate-containing solution in the presence of a physiologically acceptable gas and is stabilized by the presence of histidine.
包含用于结合KDR或VEGF/KDR复合物的靶向配体的气体填充微囊的悬浮液。所述悬浮液通过在生理学可接受气体存在下,用含碳水化合物溶液重构冻干残留物而获得,并且通过在组氨酸存在下被稳定化。 |
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Bibliography: | Application Number: CN201580068643 |