Targeted gas-filled microvesicles formulation

Suspension of gas-filled microvesicles comprising a targeting ligand for binding to KDR or VEGF/KDR complex. The suspension is obtained by reconstituting a freeze-dried residue with a carbohydrate-containing solution in the presence of a physiologically acceptable gas and is stabilized by the presen...

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Bibliographic Details
Main Authors LASSUS ANNE, BUSSAT PHILIPPE
Format Patent
LanguageChinese
English
Published 26.09.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Suspension of gas-filled microvesicles comprising a targeting ligand for binding to KDR or VEGF/KDR complex. The suspension is obtained by reconstituting a freeze-dried residue with a carbohydrate-containing solution in the presence of a physiologically acceptable gas and is stabilized by the presence of histidine. 包含用于结合KDR或VEGF/KDR复合物的靶向配体的气体填充微囊的悬浮液。所述悬浮液通过在生理学可接受气体存在下，用含碳水化合物溶液重构冻干残留物而获得，并且通过在组氨酸存在下被稳定化。
Bibliography:Application Number: CN201580068643