Method for preparing calcobutrol

The present invention provides a novel method for preparing highly pure calcobutrol using an intermediate (butrol) of gadobutrol without using highly pure gadobutrol. The present invention is capable of obtaining highly pure calcobutrol with high yield through a simple and environment-friendly proce...

Full description

Saved in:
Bibliographic Details
Main Authors LIM GEUN-JHO, YOON HOE-JIN, CHANG SUN-KI, BYEON CHANG-HO, KIM MOON-SOO
Format Patent
LanguageChinese
English
Published 29.08.2017
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:The present invention provides a novel method for preparing highly pure calcobutrol using an intermediate (butrol) of gadobutrol without using highly pure gadobutrol. The present invention is capable of obtaining highly pure calcobutrol with high yield through a simple and environment-friendly process, and thus can easily be mass produced. 本发明提供了种使用钆布醇的中间体(butrol)而不是使用高纯钆布醇制备高纯考布曲钙的新方法。本发明能够通过简单并且保护生态环境的工艺以高产率获得高纯考布曲钙，并且因此可以容易地被大量生产。
Bibliography:Application Number: CN201580054809