Beta-glucan methods and compositions that affect the tumor microenvironment

This disclosure relates to the combination of soluble beta-glucan and immune suppressionrelieving agents that affect the tumor microenvironment. Soluble beta-glucan promotes an immunostimulatory environment, which allows enhanced effectiveness of anti-angiogenics, checkpoint inhibitors including non...

Full description

Saved in:
Bibliographic Details
Main Authors BOSE NANDITA, GORDEN KEITH, GRAFF JEREMY, LEONARDO STEVEN, KANGAS TAKASHI, BYKOWSKI JONAS ADRIA, FRASER KATHRYN A, QIU XIAOHONG, CHAN ANISSA SH, OTTOSON NADINE
Format Patent
LanguageChinese
English
Published 29.08.2017
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:This disclosure relates to the combination of soluble beta-glucan and immune suppressionrelieving agents that affect the tumor microenvironment. Soluble beta-glucan promotes an immunostimulatory environment, which allows enhanced effectiveness of anti-angiogenics, checkpoint inhibitors including non-tumor targeting antibodies. 本发明涉及可溶性β-葡聚糖与影响肿瘤微环境的免疫抑制减轻剂的组合。可溶性β-葡聚糖促进免疫刺激性环境，这使得抗血管生成剂、包括非肿瘤靶向性抗体在内的检查点抑制剂的有效性提高。
Bibliography:Application Number: CN201580072494