Factor XIa inhibitors
The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibi...
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Main Authors | , , , , , , , , , , |
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Format | Patent |
Language | Chinese English |
Published |
29.08.2017
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.
本发明提供式I的化合物和包含种或多种所述化合物的药物组合物和使用所述化合物治疗或预防血栓形成、栓塞、高凝状态或纤维化变化的方法。该化合物是选择性因子XIa抑制剂或因子XIa和血浆激肽释放酶的双重抑制剂。 |
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Bibliography: | Application Number: CN201680006558 |