Influenza virus vaccines and uses thereof

• Main Authors: RADOSEVIC KATARINA, MEIJBERG JAN WILEM, DING ZHAOQING, WAGNER MICHELLE, IMPAGLIAZZO ANTONIETTA
• Format: Patent
• Language: Chinese; English
• Published: 18.08.2017
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Provided herein are multimeric influenza hemagglutinin stem domain polypeptides, methods for providing hemagglutinin stem domain polypeptides, compositions comprising the same, vaccines comprising the same and methods of their use, in particular in the detection, prevention and/or treatment of influenza. 此处提供了多种多聚体流行性感冒血球凝集素主干域多肽，用于提供多种血球凝集素主干域多肽的方法，包括这些多肽的组合物，包括这些多肽的疫苗及其使用方法，特别是在流行性感冒的检测、预防和/或治疗中的使用。