Protecting compositions for recombinattly produced factor VIII

A histidine-free composition comprising: a high purity factor VIII (r-factor VIII); arginine and/or sucrose; a surface-active agent to prevent or at least inhibit surface adsorption of factor VIII; an amount of calcium chloride for specific stabilization of factor VIII. 本发明提供种无组氨酸的组合物，所述组合物包括：高纯度因子V...

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Bibliographic Details
Main Authors RIPPNER BRITA, NILSSON ULRIKA, AGERKVIST ERENE, IVARSSON ELSA, KNUTSSON JOSEFIN
Format Patent
LanguageChinese
English
Published 18.08.2017
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A histidine-free composition comprising: a high purity factor VIII (r-factor VIII); arginine and/or sucrose; a surface-active agent to prevent or at least inhibit surface adsorption of factor VIII; an amount of calcium chloride for specific stabilization of factor VIII. 本发明提供种无组氨酸的组合物，所述组合物包括：高纯度因子VIII(r-因子VIII)；精氨酸和/或蔗糖；防止或至少抑制因子VIII的表面吸附的表面活性剂；用于因子VIII的特定稳定化的定量的氯化钙。
Bibliography:Application Number: CN201610936412